𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Hodgkin's disease in adults: Association with social factors and age at tonsillectomy. A case-control study

✍ Scribed by Luigina Bonelli; Vito Vitale; Franco Bistolfi; Marco Landucci; Paolo Bruzzi

Publisher
John Wiley and Sons
Year
1990
Tongue
French
Weight
465 KB
Volume
45
Category
Article
ISSN
0020-7136

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The relationship between socio‐economic characteristics, previous tonsillectomy, family history of cancer and risk of Hodgkin's disease (HD) was investigated in a case‐control study. One hundred and sixty patients, aged 15–78, with histologically confirmed HD, and 185 hospital controls were interviewed. A statistically significant decrease in risk of HD was observed among subjects with large sibship size (RR = 0.63, C.I. 0.46–0.86) and among those who underwent tonsillectomy prior to the age of 10 (RR = 0.46, C.I. 0.22–0.94). High educational level was associated with an increased risk of HD (RR = 6.68, C.I. 1.94–23.08). Analysis by age‐group (15–39 yrs and 40 yrs or more) confirmed the role of high educational level as a risk factor in both young and old subjects, while the protective effect of tonsillectomy at an early age seems to be confined to young subjects. Analysis by histological subtype showed a statistically significant decrease in risk of HD in large sibship size for both nodular sclerosis (NS) and mixed‐cell subtypes; the role of education and tonsillectomy was observed only for NS. These data confirm the role of social factors in HD risk and suggest a protective effect of tonsillectomy performed early in life that needs to be confirmed in larger population‐based studies.

📜 SIMILAR VOLUMES

Genetic risk factors in patients with in
Genetic risk factors in patients with inflammatory bowel disease and vascular complications: Case-control study
✍ I.E. Koutroubakis; A. Sfiridaki; G. Tsiolakidou; A. Theodoropoulou; A. Livadiota 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 84 KB 👁 2 views

## Background: Inherited risk factors have been suggested to play an important role in the pathogenesis of vascular complications of inflammatory bowel disease (ibd). the aim of the present study was to investigate the role of mutations associated with cardiovascular disease in ibd patients with or

An epidemiologic study of index and fami
An epidemiologic study of index and family infectious mononucleosis and adult Hodgkin's disease (HD): Evidence for a specific association with EBV+ve HD in young adults
✍ Freda E. Alexander; Davia J. Lawrence; June Freeland; Andrew S. Krajewski; Brian 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 86 KB 👁 3 views

## Abstract Infectious mononucleosis (IM) is an established risk factor for Hodgkin's disease (HD). A substantial minority (33%) of cases of HD have Epstein‐Barr virus (EBV) DNA within the malignant cells (are EBV^+ve^). It is unclear whether risk after IM applies specifically to EBV^+ve^ HD. We re

Incidence and risk factors for gallstone
Incidence and risk factors for gallstones in patients with inflammatory bowel disease: A large case-control study
✍ Fabrizio Parente; Luca Pastore; Stefano Bargiggia; Claudia Cucino; Salvatore Gre 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 122 KB 👁 1 views

The risk for gallstones (GD) in inflammatory bowel diseases and the factors responsible for this complication have not been well established. We studied the incidence of GD in a cohort of Crohn's disease (CD) and ulcerative colitis (UC) patients and investigated the related risk factors. A case-cont

Prevalence of conventional and lupus-spe
Prevalence of conventional and lupus-specific risk factors for cardiovascular disease in patients with systemic lupus erythematosus: A case–control study
✍ Bessant, Rupa ;Duncan, Rachel ;Ambler, Gareth ;Swanton, Jo ;Isenberg, David A. ; 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 83 KB 👁 2 views

## Abstract ## Objective Patients with systemic lupus erythematosus (SLE) are significantly more likely to experience a myocardial infarction or a stroke than age‐matched controls. We compared the prevalence of conventional and lupus‐specific risk factors in patients with SLE just before a cardiov