Hodgkin Lymphoma: A Comprehensive Overview

✍ Scribed by Andreas Engert, Anas Younes (eds.)

• Publisher: Springer International Publishing
• Year: 2015
• Tongue: English
• Leaves: 439
• Series: Hematologic Malignancies
• Edition: 2
• Category: Library

✦ Synopsis

This book examines in detail the current treatment options for first-line, relapsed, and refractory Hodgkin lymphoma and the management appropriate in special clinical circumstances, including in the elderly, pregnant women, and those with lymphocyte-predominant disease. Careful attention is devoted to the emerging individually tailored treatment strategies that are especially appealing given their potential to reduce early and late treatment side effects in this generally young patient population. In addition, clear guidance is provided on the management of Hodgkin survivors. Other topics addressed include epidemiology, pathogenesis, the role of the microenvironment, initial clinical evaluation, imaging diagnosis, use of staging systems, and prognostic factors. The second edition of Hodgkin Lymphoma: A Comprehensive Overview has been revised and updated by the key opinion leaders to reflect recent progress in the field. It will be of great value to hematologists, oncologists, and all others with an interest in Hodgkin lymphoma.

✦ Table of Contents

Front Matter....Pages i-xv
Front Matter....Pages 1-1
Epidemiology....Pages 3-26
The Role of Viruses in the Genesis of Hodgkin Lymphoma....Pages 27-43
Pathology and Molecular Pathology of Hodgkin Lymphoma....Pages 45-64
Microenvironment, Crosstalk, and Immune Escape Mechanisms....Pages 65-78
What Will We Learn from Genomics and Proteomics in Hodgkin Lymphoma?....Pages 79-92
Front Matter....Pages 93-93
Clinical Evaluation....Pages 95-106
Functional Imaging in Hodgkin Lymphoma....Pages 107-130
Prognostic Factors....Pages 131-155
Principles of Radiation Therapy for Hodgkin Lymphoma....Pages 157-176
Principles of Chemotherapy in Hodgkin Lymphoma....Pages 177-199
Treatment of Early Favorable Hodgkin Lymphoma....Pages 201-220
Treatment of Early Unfavorable HL....Pages 221-234
Treatment of Advanced-Stage Hodgkin Lymphoma....Pages 235-250
Front Matter....Pages 251-251
Pediatric Hodgkin Lymphoma....Pages 253-270
The Management of Older Patients with Hodgkin Lymphoma....Pages 271-286
Nodular Lymphocyte-Predominant Hodgkin Lymphoma....Pages 287-295
The Management of Hodgkin Lymphoma During Pregnancy....Pages 297-305
The Management of HIV-Hodgkin Lymphoma....Pages 307-318
Front Matter....Pages 319-319
Relapsed and Refractory Hodgkin Lymphoma....Pages 321-330
Allogeneic Transplantation for Relapsed Hodgkin Lymphoma....Pages 331-341
Front Matter....Pages 319-319
Targeting CD30 in Patients with Hodgkin Lymphoma....Pages 343-354
Other New Agents for Hodgkin Lymphoma....Pages 355-361
Front Matter....Pages 363-363
Quality of Life in Hodgkin Lymphoma....Pages 365-374
Second Malignancy Risk After Treatment of Hodgkin Lymphoma....Pages 375-409
Cardiovascular and Pulmonary Late Effects....Pages 411-425
Gonadal Dysfunction and Fertility Preservation in Hodgkin Lymphoma Patients....Pages 427-437

✦ Subjects

Hematology; Oncology