Hodgkin disease in children: Clinicoepidemiologic and viral (Epstein-Barr virus) analyses
✍ Scribed by �avdar, A.O.; Pamir, A.; G�zda?oglu, S.; Babacan, E.; Yavuz, G.; �nal, E.; Uluoglu, �.; Ta�yildiz, N.; ?kincio??ullar?, A.
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 200 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0098-1532
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Hodgkin's disease (HD) has long been suspected to have an infectious precursor, and indirect evidence has implicated Epstein-Barr virus (EBV), a ubiquitous herpesvirus, as a causal agent. Recent molecular studies using EBER in situ hybridization or latency membrane protein-1 (LMP-1) immunohistochemi
## BACKGROUND. The association of Epstein-Barr virus (EBV) with Hodgkin's disease (HD) is intimately related to socioeconomic status. The proportion of HD patients with EBV is high in developing countries but low in developed countries. The aim of this study was to delineate the association of EBV