HNF1Balterations associated with congenital anomalies of the kidney and urinary tract
โ Scribed by Makiko Nakayama; Kandai Nozu; Yuki Goto; Koichi Kamei; Shuichi Ito; Hidenori Sato; Mitsuru Emi; Koichi Nakanishi; Shigeru Tsuchiya; Kazumoto Iijima
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 202 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0931-041X
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Congenital anomalies of the kidney and the urinary tract (CAKUT) represent a major source of morbidity and mortality in children. Several factors (PAX, SOX,WNT, RET, GDFN, and others) play critical roles during the differentiation process that leads to the formation of nephron epithelia. We have ide
## Abstract Two young mothers of children presenting with congenital anomalies of the urinary tract underwent colectomy for carcinoma or adenomatosis of the colon. In another family with urinary anomalies, the maternal grandmother had died from carcinoma of the colon at 36 years of age. This previo