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HMGCR is necessary for the tumorigenecity of esophageal squamous cell carcinoma and is regulated by Myc

โœ Scribed by Zhong, Chenxi; Fan, Limin; Yao, Feng; Shi, Jianxin; Fang, Wentao; Zhao, Heng

Book ID
121446292
Publisher
S. Karger AG
Year
2014
Tongue
English
Weight
423 KB
Volume
35
Category
Article
ISSN
1010-4283

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โœ Rigberg, David A.; Centeno, Joseph; Kim, Frances S.; Ke, Bibo; Swenson, Kim; Mag ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 155 KB ๐Ÿ‘ 2 views

Background and Objectives: Fas (APO-1) induces apoptosis after binding Fas ligand (FasL). Evidence suggests that tumors may use this interaction to evade the host immune response. Fas/FasL expression has not been reported in esophageal cancer. We hypothesized that Fas expression would render esophag