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HMGCR gene polymorphism is associated with stroke risk in the EPIC-Norfolk study :

โœ Scribed by Freitas, Renata N.; Khaw, Kay-Tee; Wu, Kelvin; Bowman, Richard; Jeffery, Hannah; Luben, Robert; Wareham, Nick J.; Rodwell, Sheila


Book ID
115540823
Publisher
Lippincott Williams and Wilkins
Year
2010
Tongue
English
Weight
207 KB
Volume
17
Category
Article
ISSN
1741-8267

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A polymorphism in the CYP17 gene is asso
โœ Andrea Gsur; Gabriele Bernhofer; Sonja Hinteregger; Gerald Haidinger; Georg Scha ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 63 KB ๐Ÿ‘ 2 views

CYP17 encodes the enzyme cytochrome P-450c17โฃ, which mediates both 17โฃ-hydroxylase and 17,20-lyase in the steroid biosynthesis pathway. A polymorphism in the 5 promoter region of the CYP17 gene has been described. Steroid hormones, especially androgens, are believed to play a key role in the etiolog