Using liver allografts with warm or cold ischemia, we evaluated functional and morphological alterations in hepatocytes, sinusoidal endothelial cells and Kupffer cells in a rat transplantation model. All recip ients of allografts with either 4 hr of cold or 30 min of warm ischemia lived more than 22
HMGB1 in ischemic and non-ischemic liver after selective warm ischemia/reperfusion in rat
β Scribed by Anding Liu; Olaf Dirsch; Haoshu Fang; Jian Sun; Hao Jin; Wei Dong; Uta Dahmen
- Book ID
- 106100326
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 600 KB
- Volume
- 135
- Category
- Article
- ISSN
- 1432-119X
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The effect of a localized hepatic injury, regional ischemia/reperfusion, on the expression of connexin 32 (Cx32) was studied. Cx32 is the component of the major hepatic gap junction. Two regions of the injured liver were analyzed: the area directly affected by the ischemic insult (ischemic liver), a
## 5 Fe Β΄de Β΄ration d
Hepatic damage following ischemia-reperfusion injury involves polymorphonuclear leukocytes (PMN) and platelet sequestration, however the mechanisms of adhesion remain elusive. In this study, using gene-targeted deficient mice, we evaluated P-selectin and its contribution to PMN and platelet adhesion