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HMGB1, a novel inflammatory cytokine

โœ Scribed by Shingo Yamada; Ikuro Maruyama


Book ID
116347353
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
401 KB
Volume
375
Category
Article
ISSN
0009-8981

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## Abstract High mobility __g__roup __b__ox 1 (HMGB1) is a chromatin protein that acts as an immunomodulatory cytokine upon active release from myeloid cells. HMGB1 is also an alarmin, an endogenous molecule released by dying cells that acts to initiate tissue repair. We have previously reported th