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Hmga1 is differentially expressed and mediates silencing of the CD4/CD8 loci in T cell lineages and leukemic cells

✍ Scribed by Yang Xi; Sugiko Watanabe; Yuko Hino; Chiyomi Sakamoto; Yuko Nakatsu; Seiji Okada; Mitsuyoshi Nakao

Book ID
114703137
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
483 KB
Volume
103
Category
Article
ISSN
1347-9032

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The pan-NK cell marker NK1.1, present in some mouse strains, is also found on a subset of TCRalphabeta+ lymphocytes termed NKT cells. These cells are primarily CD4+ or CD4-CD8- (double negative, DN), and both NKT subpopulations contain cells reactive with the MHC class I-like molecule CD1d. Murine N