The conformation of the DNA and the interactions of the nucleic acid with the protein in a complex of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) and a 19-mer/18-mer double-stranded DNA template-primer (dsDNA) are described. The structure of this HIV-1 RT complex with dsDN
✦ LIBER ✦
HMGA proteins as therapeutic drug targets: interaction of DNA with human HMGA1a
✍ Scribed by N. Saperas; R. Sánchez-Giraldo; E. Fonfría-Subirós; G. Sanahuja; M. Pagán; S. Rodríguez-Puente; J.L. Campos
- Publisher
- Elsevier
- Year
- 2009
- Tongue
- English
- Weight
- 71 KB
- Volume
- 25
- Category
- Article
- ISSN
- 1871-6784
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## Abstract Using dithioester‐capped 2‐methacryloyloxyethyl phosphorylcholine (MPC) as a macro chain transfer agent, a diblock copolymer was synthesized with __n__‐butyl methacrylate (BMA) as hydrophobic core‐forming blocks. The MPC–BMA unit was copolymerized with an immobilizable unit, __p__‐nitro