𝔖 Bobbio Scriptorium
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HMG CoA reductase inhibitor [statin] therapy is associated with reduced restenosis rates


Book ID
120865989
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2001
Weight
151 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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## Abstract Apomine, a novel 1,1 bisphosphonate ester, increases the rate of degradation of HMG‐CoA reductase, inhibiting the mevalonate pathway and thereby blocking cholesterol biosynthesis. We have investigated whether Apomine can induce myeloma cell apoptosis __in vitro__ and modulate myeloma di