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HMG-CoA reductase inhibitor-induced L6 myoblast cell death: involvement of the phosphatidylinositol 3-kinase pathway

✍ Scribed by Hiroto Nakagawa; Tatsuro Mutoh; Takanori Kumano; Masaru Kuriyama

Book ID: 117109950
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 119 KB
Volume: 438
Category: Article
ISSN: 0014-5793
DOI: 10.1016/s0014-5793(98)01320-9

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## Abstract Excitotoxicity and cell death induced by glutamate are involved in many neurodegenerative disorders. We have previously demonstrated that excitotoxicity induced by millimolar concentrations of glutamate in hippocampal slices involves apoptotic features and glutamate‐induced glutamate re