✦ LIBER ✦

HLA typing does not predict REM sleep behaviour disorder and hallucinations in Parkinson's disease

✍ Scribed by Marco Onofrj; Anna Lisa Luciano; Diego Iacono; Astrid Thomas; Fabrizio Stocchi; Franco Papola; Domenico Adorno; Rocco Di Mascio

Publisher: John Wiley and Sons
Year: 2003
Tongue: English
Weight: 60 KB
Volume: 18
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.10409

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✦ Synopsis

Abstract

HLA‐DR2 haplotype and DQ1 DNA alleles, characterizing 90 to 100% of all narcoleptic patients, were found to be equally distributed in 20 Parkinson's disease (PD) patients with early hallucinations, rapid eye movement (REM) sleep‐related behaviour disturbances (RBD), and sleep onset in REM (SOREM), and in 20 PD patients without hallucinations, despite 10 to 15 years of treatment, and no RBD or SOREM.

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REM sleep behavior disorder, hallucinations, and cognitive impairment in Parkinson's disease

✍ Elena Sinforiani; Roberta Zangaglia; Raffaele Manni; Silvano Cristina; Enrico Ma 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 58 KB

## Abstract The objective of this study was to evaluate the relationship between REM sleep behavior disorder (RBD), hallucinations, and cognitive impairment in Parkinson's disease (PD). One hundred and ten PD patients, divided into three groups (without RBD or hallucinations; with RBD but no halluc