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HLA-G expression in human melanoma cells: protection from NK cytolysis

✍ Scribed by Francisco Adrián Cabestré; Philippe Moreau; Béatrice Riteau; El Chérif Ibrahim; Caroline Le Danff; Jean Dausset; Nathalie Rouas-Freiss; Edgardo D Carosella; Pascale Paul

Book ID: 114133174
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 238 KB
Volume: 43
Category: Article
ISSN: 0165-0378
DOI: 10.1016/s0165-0378(99)00037-6

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Considerable information has been accumulated on HLA-G expression in tumor lesions in which HLA-G is viewed as a way to turn off anti-tumoral immunity. Nevertheless, there is little data concerning the mechanisms by which expression and function of HLA-G are regulated in malignant cells. Here, we ha