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HLA-DR4 in Insulin-Dependent Diabetic Parents and Their Diabetic Offspring: A Clue to Dominant Inheritance

✍ Scribed by Michael J. MacDonald, Jerry Gottschall, Jay B. Hunter and Karen L. Winter


Book ID
123633361
Publisher
National Academy of Sciences
Year
1986
Tongue
English
Weight
878 KB
Volume
83
Category
Article
ISSN
0027-8424

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πŸ“œ SIMILAR VOLUMES


HLA DR4-DQw3.1 and 3.2 haplotypes among
✍ Dr. Kathryn J. Gogolin; Richard S. Spielman πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 288 KB

Almost all human leukocyte antigen (HLA) haplotypes positive for HLA-DR4 also cany the DQw3 specificity, which appears in one of two allelic forms, DQw3.1 or DQw3.2. Previous studies have shown that the frequency of the HLA DR4-DQw3.2 allele is approximately 95 % among DR4-positive haplotypes of ins