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HLA-DR molecules enhance signal transduction through the CD3/Ti complex in activated T cells

✍ Scribed by Niels Ødum; Paul J. Martin; Gary L. Schieven; Susan Masewicz; John A. Hansen; Jeffrey A. Ledbetter

Book ID
115096125
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
601 KB
Volume
38
Category
Article
ISSN
0001-2815

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## HLA class I1 molecules on monocytes regulate T cell proliferation through physical interaction in the CD3 activation pathway* HLA class I1 molecules are involved in the OKT3-induced Tcell activation, since monoclonal antibodies (mAb) to monomorphic determinants of class I1 antigens are able to