The results of two epidemiological studies suggest a hereditary predisposition to develop drug-induced parkinsonism. We investigated human leukocyte antigen (HLA) antigen prevalence rates in patients with neurolepticinduced parkinsonism. Fifty-two male, white, neuroleptic-treated, chronic inpatients
HLA-DR antigens in gold-induced neutropenia
β Scribed by Dr. Stephen Aaron; Paul Davis; James Bertouch
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 275 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0004-3591
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The central feature of a number of connective tissue or "autoimmune" disorders is widespread vascular inflammation. Although many of the resulting clinical and serologic abnormalities nonspecifically reflect tissue injury, sufficient variation exists in the pathology, type of organ involvement, and
Table 1. Demographic and epidemiologic features in white rheumatoid arthritis patients receiving gold treatment Toxicity Number of patients Mean age 2 SD Mean age at onset \* SD (years) Mean duration of disease 2 SD (years) Males (%) Females 1%) Seropositive (%) Present Absent 38 59.8 2 11.5 45.0 2