✦ LIBER ✦

HLA-DQα allele and genotype frequencies in a native Kuwaiti population

✍ Scribed by Khaled E. Al-Nassar; Jancy Mathew; Nancy Thomas; Hasmukh R. Fatania

Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 282 KB
Volume: 72
Category: Article
ISSN: 0379-0738
DOI: 10.1016/0379-0738(94)01618-f

No coin nor oath required. For personal study only.

✦ Synopsis

We report the allele and genotype frequencies in a sample of an unrelated native Kuwaiti population determined by the use of polymerase chain reaction (PCR) and reverse dot-blot analysis. This technique, involving the use of commercially available AmpliType HLA-DQa forensic DNA amplification and typing kit, has permitted the definition of six alleles and 21 genotypes in a sample of 220 people. The allelic frequencies are in the range 5.7-27.5%. This locus demonstrated a heterozygosity of 0.80 with an allelic diversity of 0.81 and the power of discrimination (PD) was 0.93. The distribution of observed genotypes conformed to Hardy-Weinberg equilibrium thus indicating genetic equilibrium of the different variants. This population data should permit the use of HLA-DQar marker for individual identification in forensic casework.

📜 SIMILAR VOLUMES

HLA-DQA1 allele and genotype frequencies

HLA-DQA1 allele and genotype frequencies in a Northern Italian population

✍ F. De Stefano; L. Casarino; A. Mannucci; L. Delfino; M. Canale; G.B. Ferrara 📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 694 KB

HLA-DQA1 typing of 227 randomly selected Northern Italian people by the use of polymerase chain reaction are reported. The combined use of commercial Amplitype HLA-DQalpha system and four sequence-specific oligonucleotide probes allows the definition of 8 alleles and 36 genotypes, arranged according

Frequency of D1S80 and HLA DQα alleles i

Frequency of D1S80 and HLA DQα alleles in a Chinese population

✍ Jian Tie; Shigemi Oshida; Shoetsu Chiba; Shojiro Tsukamoto; Ismail M. Sebetan 📂 Article 📅 1995 🏛 Springer-Verlag 🌐 German ⚖ 119 KB

Characterisation of HLA DQα for forensic

Characterisation of HLA DQα for forensic purposes. Allele and genotype frequencies in British Caucasian, Afro-Caribbean and Asian populations

✍ K. M. Sullivan; P. Gill; D. Lingard; J. E. Lygo 📂 Article 📅 1992 🏛 Springer-Verlag 🌐 German ⚖ 443 KB

Allele Frequencies and Molecular Genotyp

Allele Frequencies and Molecular Genotyping of the ABO Blood Group System in a Kuwaiti Population

✍ Suzanne Al-Bustan; Mokhtar El-Zawahri; Daleil Al-Azmi; Abdul-Aziz Al-Bashir 📂 Article 📅 2002 🏛 Carden Jennings Publishing 🌐 English ⚖ 552 KB

?-fibrinogen allele frequencies in Peruv

?-fibrinogen allele frequencies in Peruvian Quechua, a high-altitude native population

✍ Rupert, Jim L.; Devine, Dana V.; Monsalve, M. Victoria; Hochachka, Peter W. 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 94 KB

Elevated hematocrits, which are found in many high-altitude populations, increase the oxygen-carrying capacity of blood and may represent an adaptation to hypoxic environments. However, as high hematocrit increases blood viscosity, which in turn is associated with hypertension and heart disease, it

The distribution of the HLA-DQα alleles

The distribution of the HLA-DQα alleles and genotypes in the Turkish Population as determined by the use of DNA amplification and allele-specific oligonucleotides

✍ S. Menevse; Ü. Ülküer 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 361 KB

Allele and genotype frequencies for the HLA-DQa locus were determined for use in forensic analyses in Turkey. The polymerase chain reaction and the reverse dot blot format were employed to detect six different HLA DQa alleles, which were detected among 150 unrelated individuals with allele frequenci