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HLA-DP/DRinteraction in children with juvenile rheumatoid arthritis

✍ Scribed by Catherine Kerckhove; Lorie Luyrink; Maruja S. Elma; Walter P. Maksymowych; Joseph E. Levinson; Martin G. Larson; Edmund Choi; David N. Glass


Publisher
Springer-Verlag
Year
1990
Tongue
English
Weight
410 KB
Volume
32
Category
Article
ISSN
0093-7711

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We investigated the polymorphic second exon of the HLA-DPB1 and HLA-DRB1 genes, using in vitro DNA amplification by polymerase chain reaction (PCR) and oligonucleotide hybridization in 136 patients with early onset pauciarticular juvenile chronic arthritis (EOPA-JCA) and 199 healthy controls. The an

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## Objective: To examine demographic and disease-related variables that affect pain in a large cohort of patients with juvenile rheumatoid arthritis (jra). ## Methods: Selection criteria were an onset of jra >/=5 years prior to study and age >/=8 years at the time of the study. pain was measured