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HLA class-I-specific inhibitory receptor in human T lymphocytes: Interference with T-cell functions

โœ Scribed by M.C. Mingari; M. Ponte; C. Vitale; F. Schiavetti; R. Bellomo; S. Bertone; L. Nanni


Book ID
117614812
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
541 KB
Volume
148
Category
Article
ISSN
0923-2494

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MHC class-1-specific inhibitory receptors were originally described in NK cells, in which they represent an important fail-safe mechanism that induces NK cell tolerance to normal self cells. These inhibitory NK receptors (iNKRs) were subsequently found expressed on different T cell subsets, primaril