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HLA class I antigen loss, tumor immune escape and immune selection

✍ Scribed by Michael Campoli; Chien-Chung Chang; Soldano Ferrone

Book ID
117431113
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
235 KB
Volume
20
Category
Article
ISSN
0264-410X

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## Abstract Oncogenic transformation in human and experimental animals is not necessarily followed by the appearance of a tumor mass. The immune system of the host can recognize tumor antigens by the presentation of small antigenic peptides to the receptor of cytotoxic T‐lymphocytes (CTLs) and reje