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HLA class I and neuroendocrine antigen expression in multidrug resistant small cell lung carcinoma cell lines

Book ID
122475454
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
152 KB
Volume
16
Category
Article
ISSN
0169-5002

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HLA class I molecules present antigenic peptides to cytotoxic T lymphocytes and thus play an important role in immune surveillance of cells infected with virus or altered by malignant transformation. Immunochemical studies have demonstrated a marked deficiency or lack of expression of class I molecu

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HLA class I antigens of the human major histocompatibility complex (MHC) play an important role in immune response. Consistent with their role in immune surveillance, these antigens are expressed on most cell types. However, a marked deficiency or lack of expression of these antigens has been observ