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HLA-antigens in systemic lupus erythematosus (SLE)

โœ Scribed by Dieter Kampf; Reinhard Malchus; Meta Alexander; Immo Hoppe

Publisher
Springer-Verlag
Year
1979
Tongue
English
Weight
350 KB
Volume
264
Category
Article
ISSN
0340-3696

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โœฆ Synopsis

Histocompatibility antigens were determined in 27 patients with SLE and 283 normal blood donors. HLA-B8 was significantly increased in patients with SLE (59.3%) as compared to the controls (20.5%, Pc less than 0.005). The relative risk for HLA-B8 was 5.64. No correlation could be demonstrated to specific organ involvement, immunopathological data, age of onset or prognosis.

๐Ÿ“œ SIMILAR VOLUMES

DNA typing of HLA-DR antigens in systemi
DNA typing of HLA-DR antigens in systemic lupus erythematosus
โœ H. Dunckley; P. A. Gatenby; S. W. Serjeantson ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 475 KB

HLA-DR typing is technically difficult in systemic lupus erythematosus (SLE), where patients have low numbers of peripheral B cells, often of poor viability and weak in antigenic expression. In this series, one third of SLE patients could not be HLA-DR typed by serological techniques, highlighting t