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HLA antigen frequencies in patients with huntington's chorea and their relatives

✍ Scribed by K. Foerster; J. Freudenberg

Publisher
Springer
Year
1980
Tongue
English
Weight
267 KB
Volume
223
Category
Article
ISSN
0340-5354

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✦ Synopsis

Twenty patients with Hungtington's chorea and 30 family members were typed for 30 antigens of the HLA-A, B, and C series. There was an increased frequency of HLA-BW 16, significant at the 1%-level. After correcting for multiple inferences, the association of HLA-BW 16 with Huntington's chorea was no longer statistically significant. There was also no reliable indication of coupling between HLA antigens and Huntington's chorea in the family studies.

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