𝔖 Bobbio Scriptorium
✦   LIBER   ✦

HLA and type I diabetes

✍ Scribed by Gerald T. Nepom

Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
427 KB
Volume
11
Category
Article
ISSN
0167-5699

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✦ Synopsis

In next month's Immunology Today

* Haemopoietic receptors and helical cytokines * HIV and B-cell activation * Tolerance and the thymic epithelium * Cognate T H-B interactions * T-cell recoqnition of the antigen~MHC complex

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Interaction of HLA and immunoglobulin an
Interaction of HLA and immunoglobulin antigens in Type 1 (insulin-dependent) diabetes
✍ L. L. Field; C. E. Andersen; K. Neiswanger; S. E. Hodge; M. A. Spence; J. I. Rot πŸ“‚ Article πŸ“… 1984 πŸ› Springer 🌐 English βš– 657 KB

We analyzed 88 unrelated subjects with Type 1 (insulin-dependent) diabetes and 64 sibling controls (maximum one per diabetic) for associations between immunoglobulin allotype antigens (GM and KM) and Type 1 diabetes. None were found. However, we did find interactions between GM, HLA-DR, and Type 1 d

Modeling of HLA class II susceptibility
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## Abstract In this report, we present evidence that the HLA class II DPB1 locus (or a locus with alleles in linkage disequilibrium with DPB1) contributes to Type I diabetes (IDDM) susceptibility in addition to the contribution of the HLA DR and DQ loci. The marker association segregation chi‐squar