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HLA and altered sex ratios in juvenile rheumatoid arthritis sibships

✍ Scribed by Van Kerckhove, Catherine; Balakrishnan, Kamala; Levinson, Joseph E.; Larson, Martin G.; Glass, David N.

Book ID
123428763
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
304 KB
Volume
22
Category
Article
ISSN
0198-8859

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There is a well-known association between rheumatoid arthritis (RA) and HLA-DR4. Recent research has indicated that both DR4 haplotypes are important in disease predisposition (favoring a recessive mode of inheritance). Others have suggested that certain combinations of genotypes, in particular Dw4/