HIV/AIDS-Associated Viral Oncogenesis

✍ Scribed by Craig Meyers

• Publisher: Springer International Publishing
• Year: 2019
• Tongue: English
• Leaves: 252
• Series: Cancer Treatment and Research 177
• Edition: 2nd ed.
• Category: Library

✦ Synopsis

In this book, leading experts examine the clinical and biological aspects of viruses known to play a role in the oncogenesis of AIDS-associated cancers and non-AIDS-defining malignancies more commonly observed in HIV-infected individuals. Among the malignancies considered are those associated with Kaposi sarcoma-associated herpesvirus (KSHV) or Epstein–Barr virus (EBV), Merkel cell carcinoma due to Merkel cell polyomavirus (MCPyV), human papillomavirus (HPV)-associated anogenital and oropharyngeal cancers, and hepatitis B and C virus (HBV/HCV)-associated liver cancers. It also provides detailed information on the molecular biology of the causative viral agents and guidance on the specific treatment required in this special population. Covering all the important advances in our understanding made since the first edition was published in 2007, including the discovery and characterization of MCPyV, which brought the number of known human oncoviruses to seven, this new edition is a valuable resource for members of the scientific and healthcare community and active researchers in this field.

✦ Table of Contents

Front Matter ....Pages i-viii
AIDS-Associated Malignancies (Ramya Vangipuram, Stephen K. Tyring)....Pages 1-21
Molecular Biology of KSHV in Relation to HIV/AIDS-Associated Oncogenesis (Meilan He, Fan Cheng, Suzane Ramos da Silva, Brandon Tan, Océane Sorel, Marion Gruffaz et al.)....Pages 23-62
Kaposi’s Sarcoma-Associated Herpesvirus (KSHV)-Associated Disease in the AIDS Patient: An Update (Dirk P. Dittmer, Blossom Damania)....Pages 63-80
Molecular Biology of EBV in Relationship to HIV/AIDS-Associated Oncogenesis (Fengchao Lang, Yonggang Pei, Zachary L. Lamplugh, Erle S. Robertson)....Pages 81-103
Human Papillomavirus Infection and Cervical Cancer in HIV+ Women (Ping Du)....Pages 105-129
HPV-Associated Oropharyngeal Cancer in the HIV/AIDS Patient (Jennifer E. Cameron, Michael Hagensee)....Pages 131-181
HPV-Associated Anal Cancer in the HIV/AIDS Patient (Chia-Ching J. Wang, Joel M. Palefsky)....Pages 183-209
Merkel Cell Carcinoma in the HIV-1/AIDS Patient (Robert H. Goldstein, James A. DeCaprio)....Pages 211-229
HIV–HBV and HIV–HCV Coinfection and Liver Cancer Development (Jianming Hu, Kuancheng Liu, Jun Luo)....Pages 231-250

✦ Subjects

Medicine & Public Health; Oncology; Infectious Diseases; Immunology; Virology