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HIV resistance to zidovudine: the role of pyrophosphorolysis

✍ Scribed by Dominique Arion; Michael A. Parniak

Book ID
117836107
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
121 KB
Volume
2
Category
Article
ISSN
1368-7646

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The development of mutations conferring drug resistance was investigated in 49 antiretroviralnaive asymptomatic HIV-1 subjects with CD4 + cell counts of 250-500/mm 3 given intermittent (6-week courses, 6 weeks apart) or continuous treatment with zidovudine (AZT) plus zalcitabine (ddC) over 54 weeks.