Hemochromatosis is an autosomal recessive disease of iron metabolism, characterized by progressive iron loading in parenchymal cells of the major organs of the body. This iron overload may result in cirrhosis, diabetes, cardiac failure and arrythmia, hypogonadism, arthritis, hepatocellular carcinoma
HIV Recent advances in AIDS research: genetics, molecular biology and immunology
β Scribed by Nathaniel R Landau
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 263 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0952-7915
No coin nor oath required. For personal study only.
β¦ Synopsis
Forty years after what is believed to have been its initial jump from primate to man [l], HIV continues to spread through the human population, opening new fronts in India and elsewhere in Asia-often impacting those groups least able to confront the problem politically, socially or medically. Often, social pressures prohibit even facing the issue. This is an extremely dangerous response, since ignoring this problem only magnifies it. In the developed world, most symptomatic patients are treated with an expensive antiviral cocktail that targets critical components of the virus. This treatment has increased the length and quality of infected individuals' lives but ultimately may not prevent them from succumbing to the immune system ravages caused by the virus.
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Adenosine is a hydrophilic molecule that requires specialized transport proteins for permeation of cell membranes. Functional studies have identified two types of nucleoside transport processes: equilibrative bidirectional processes driven by chemical gradients and inwardly directed concentrative pr