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HIV mutagenesis and the evolution of antiretroviral drug resistance

✍ Scribed by Louis M. Mansky


Book ID
117764489
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
70 KB
Volume
5
Category
Article
ISSN
1368-7646

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We studied the relationship between recombination and the fixation time of multiple drug resistance mutations after HIV-1 drug therapy, under a set of different realistic scenarios. We have generalized a previous model by Bretscher et al. [Bretscher, Althaus, Muller, Bonhoeffer, 2004. Recombination