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HIV infection and protease genetic diversity in a rural area of the Southern Central African Republic

✍ Scribed by Grazia Punzi; Annalisa Saracino; Gaetano Brindicci; Teresa Scarabaggio; Antonella Lagioia; Gioacchino Angarano; Laura Monno

Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 59 KB
Volume: 77
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.20476

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✦ Synopsis

Thirty-eight of 175 (21.7%) consecutive women of childbearing age from a rural area near Bangassou were tested HIV-positive. Ten protease and two protease/reverse transcriptase sequences (31.5% samples) were obtained. Eight sequences clustered into subtype J, A, G; two sequences were 13_cpx recombinant forms and two were indeterminate. The high proportion of HIV found suggests a recent outbreak of diversified HIV strains.

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## Abstract The prevalence of hepatitis C virus (HCV) antibodies, HCV infection, and genotypes was studied in a rural population of the Central African Republic. In five villages, blood samples were taken from all the inhabitants present during the survey, belonging to Pygmies (299) and to Bantu an