## Abstract In the past 25 years, the worldwide AIDS epidemic has grown such that roughly 38 million people were estimated to be living with the disease worldwide at the end of 2003. The introduction of antiretroviralβbased therapies, beginning in 1987, has enabled many to live with HIV as a chroni
β¦ LIBER β¦
HIV fusion inhibitors
β Scribed by M. I. Qadir; S. A. Malik
- Book ID
- 104590691
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 264 KB
- Volume
- 20
- Category
- Article
- ISSN
- 1052-9276
- DOI
- 10.1002/rmv.631
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β¦ Synopsis
Abstract
Drugs based on amino acid sequence of Heptad Repeats of gp41 of HIV have been explored in search of antiβHIV drugs acting by inhibition of the gp41 6βhelix formation and subsequent cellular infection. These are classified under a distinct discipline called HIV fusion inhibitors. Resistance to HIV fusion inhibitors and their solutions have also been discussed in this review. Copyright Β© 2009 John Wiley & Sons, Ltd.
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