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HIV-1 Vpr-induced cell death in Schizosaccharomyces pombe is reminiscent of apoptosis

โœ Scribed by Huard, Sylvain; Chen, Mingzhong; Burdette, Kristen E; Fenyvuesvolgyi, Csaba; Yu, Min; Elder, Robert T; Zhao, Richard Y


Book ID
109846827
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
915 KB
Volume
18
Category
Article
ISSN
0007-0610

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HIV-1, the etiologic agent of human AIDS, causes cell death in host and non-host cells via HIV-1 Vpr, one of its auxiliary gene product. HIV-1 Vpr can also cause cell cycle arrest in several cell types. The cellular processes that link HIV-1 Vpr to the cell death machinery are not well characterized