HIV-1 Tat-peptide inhibits protein kinase C and protein kinase A through substrate competition
✍ Scribed by Elina Ekokoski; Olli Aitio; Kid Törnquist; Jari Yli-Kauhaluoma; Raimo K. Tuominen
- Book ID
- 113592305
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 438 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0928-0987
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Peptides, obtained by gradual removal of amino acids from both ends of pEKRPSQRSKYL, and stereoisomeric nonapeptides KRPSQRAKY with one D-amino acid residue successively in each position, were tested as substrates for protein kinase A. All these compounds were phosphorylated but at quite different r