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HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression

✍ Scribed by Pitcher, Christine J.; Quittner, Claudia; Peterson, Dolores M.; Connors, Mark; Koup, Richard A.; Maino, Vernon C.; Picker, Louis J.


Book ID
109829828
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
728 KB
Volume
5
Category
Article
ISSN
1078-8956

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## Abstract Human immunodeficiency virus type 1 (HIV‐1) infection is characterized by a progressive decrease of CD4^+^ T cells accompanied by other immune dysfunctions. Telomerase is transiently activated in lymphocytes during activation and is able to compensate for the progressive telomeric loss