Vav exchange factor counteracts the HIV-
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Loretta Tuosto; Barbara Marinari; Mauro Andreotti; Maurizio Federico; Enza Picco
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Article
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2003
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John Wiley and Sons
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English
โ 339 KB
Several findings support the importance of GM1-enriched lipid microdomains of plasma membrane and of Vav, an essential regulator of actin cytoskeletal rearrangement, in the regulation of T cell activation. Moreover, a functional link among lipid microdomains, Vav and the HIV product Nef has been des