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HIV-1 long terminal repeat modulation by glucocorticoids in monocytic and lymphocytic cell lines

✍ Scribed by Fernanda O Russo; Pravin C Patel; Armando M Ventura; Carlos A Pereira


Book ID
117366715
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
204 KB
Volume
64
Category
Article
ISSN
0168-1702

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In the human immunodeficiency virus type 1 (HIV-1)-infected brain, the virus does not replicate in astrocytes, but a synthesis of viral regulatory proteins occurs in these cells, leading to accumulation of Nef. As an approach to understand the effects of Nef on astrocyte functional activity, we anal