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HIV-1 Auxiliary Proteins: Making Connections in a Dying Cell

✍ Scribed by Bryan R Cullen

Book ID
117268214
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
164 KB
Volume
93
Category
Article
ISSN
0092-8674

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HIV-1, the etiologic agent of human AIDS, causes cell death in host and non-host cells via HIV-1 Vpr, one of its auxiliary gene product. HIV-1 Vpr can also cause cell cycle arrest in several cell types. The cellular processes that link HIV-1 Vpr to the cell death machinery are not well characterized