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History of tonsillectomy and appendectomy in Hodgkin's disease

✍ Scribed by Z. Gledovic; Z. Radovanovic


Publisher
Springer
Year
1991
Tongue
English
Weight
335 KB
Volume
7
Category
Article
ISSN
0393-2990

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✦ Synopsis


The study comprised all 113 clinically and histologically confirmed cases of Hodgkin's disease aged 15-39 years who were treated at the Department of Hematology of the Faculty of Medicine in Belgrade from January, 1 to June, 30, 1987. For each patient, two individually matched controls were selected. Neighbourhood controls were the first neighbours of the same sex, age, and residence history. Hospital controls consisted of accidentally injured individuals, and they were matched in terms of sex, age, place of residence, and educational level. Comparison of cases and controls revealed that removal of the lymphoid tissue (either tonsils or appendix) did not affect the risk of developing Hodgkin's disease in any way. An association found by some previous studies has been explained by the confounding effect of socioeconomic status.


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Although some studies have linked excess of Hodgkin's disease (HD) to tonsillectomy, the findings have not been consistent. In particular, risk of HD by age at tonsillectomy has not been fully evaluated, despite the notable change in immunologic function of the tonsils between childhood and adulthoo