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Histone trimethylation at H3K4, H3K9 and H4K20 correlates with patient survival and tumor recurrence in early-stage colon cancer

✍ Scribed by Anne Benard,Inès J Goossens-Beumer,Anneke Q van Hoesel,Wouter de Graaf…

Book ID
126371270
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
768 KB
Volume
14
Category
Article
ISSN
1471-2407

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✍ Konstantin Lepikhov; Jörn Walter 📂 Article 📅 2004 🏛 BioMed Central 🌐 English ⚖ 623 KB

## Background In the mouse zygote the paternal genome undergoes dramatic structural and epigenetic changes. Chromosomes are decondensed, protamines replaced by histones and DNA is rapidly and actively demethylated. The epigenetic asymmetry between parental genomes remains at least until the 2-cell