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Histone deacetylases: complex transducers of nuclear signals

✍ Scribed by Colin A. Johnson; Bryan M. Turner

Book ID
115647455
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
471 KB
Volume
10
Category
Article
ISSN
1084-9521

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## Abstract Histone deacetylase (HDAC) activity was first discovered about 40 years ago, but it was not until the molecular identification of the first HDACs in 1996 that this family of enzymes gained prominence. In addition to histones, HDACs reverse lysine acetylation of various non‐histone prote