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Histone Deacetylases Associated with the mSin3 Corepressor Mediate Mad Transcriptional Repression

โœ Scribed by Carol D Laherty; Wen-Ming Yang; Jian-Min Sun; James R Davie; Edward Seto; Robert N Eisenman


Book ID
117267214
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
229 KB
Volume
89
Category
Article
ISSN
0092-8674

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## Abstract Gfiโ€1 and Gfiโ€1B can repress transcription and play important roles in hematopoietic cell survival and differentiation. Although these proteins are known to bind DNA through a Cโ€terminal zincโ€finger domain and may require an Nโ€terminal SNAG domain (SNAIL/Gfiโ€1) to repress transcription,