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Histone Deacetylase Inhibitors Transcriptionally Regulate Notch1 Expression in Neuroendocrine Malignancies

โœ Scribed by M. Roy; R. Jaskula-Sztul; S.N. Pinchot; P. Pisarnturakit; M. Kunnimalaiyaan; H. Chen


Book ID
116706030
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
73 KB
Volume
158
Category
Article
ISSN
0022-4804

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Regulation of CYP1A2 by histone deacetyl
โœ Bohwan Jin; Doug-Young Ryu ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 58 KB

## Abstract Cytochrome P450 1A2 (CYP1A2) is constitutively expressed in the mouse liver, but the constitutive expression progressively declines to an undetectable level in isolated hepatocytes. In this study, CYP1A2 was induced in hepatocytes exposed to the histone deacetylase inhibitors trichostat