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Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia

✍ Scribed by Herman, David; Jenssen, Kai; Burnett, Ryan; Soragni, Elisabetta; Perlman, Susan L; Gottesfeld, Joel M


Book ID
109914105
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
233 KB
Volume
2
Category
Article
ISSN
1552-4450

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## Abstract Telomerase activity is involved in cellular immortality. We have recently demonstrated that telomerase activity is closely associated with cell proliferation in prostate cancers. Telomerase is composed primarily of the catalytic subunit (hTERT) and the RNA template (hTERC), and __hTERT_