## Abstract Valproic acid (VPA) has been used as an anticonvulsant agent for the treatment of epilepsy, as well as a mood stabilizer for the treatment of bipolar disorder, for several decades. The mechanism of action for these effects remains to be elucidated and is most likely multifactorial. Rece
Histone deacetylase inhibitors decrease proliferation potential and multilineage differentiation capability of human mesenchymal stem cells
β Scribed by S. Lee; J-R. Park; M-S. Seo; K-H. Roh; S-B. Park; J-W. Hwang; B. Sun; K. Seo; Y-S. Lee; S-K. Kang; J-W. Jung; K-S. Kang
- Book ID
- 108677936
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 1013 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0960-7722
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## Abstract Histone deacetylase inhibitors (HDACis) have received considerable attention for their antiβtumoral properties. We report here the effects of two HDACis, SAHA and MSβ275, on the biology of mesenchymal stem cells (MSCs). It is well known that HDACis trigger both DNA damage responses and
## Abstract Pulsed electromagnetic fields (PEMFs) have been used clinically to slow down osteoporosis and accelerate the healing of bone fractures for many years. The aim of this study is to investigate the effect of PEMFs on the proliferation and differentiation potential of human bone marrow mese