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Histone acetylation: a gateway to transcriptional activation

✍ Scribed by Rolf Sternglanz

Book ID: 114327654
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 233 KB
Volume: 21
Category: Article
ISSN: 0968-0004
DOI: 10.1016/s0968-0004(96)30034-0

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## Abstract Transcriptional repression and silencing have been strongly associated with hypoacetylation of histones. Accordingly, histone deacetylases, which remove acetyl groups from histones, have been shown to participate in mechanisms of transcriptional repression. Therefore, current models of