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Histomorphometric study of the healing of human oral mucosa after gingivoplasty and low-level laser therapy

✍ Scribed by Carla A. Damante; Sebastião L.A. Greghi; Adriana C.P. Sant'Ana; Euloir Passanezi; Rumio Taga


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
495 KB
Volume
35
Category
Article
ISSN
0196-8092

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✦ Synopsis


Abstract

Background and objectives

The aim of the present study was to analyze the effects of diode laser irradiation on the healing of human oral mucosa.

Materials and Methods

After gingivoplasty, the right hemi‐arch (test group) of 16 patients was irradiated with a diode laser. The left side (control group) was not irradiated. Incisional biopsies were performed on both sides at 7, 14, 21, and 60 days after surgery and morphometrically analyzed by light microscopy.

Results

Epithelium width ranged from 260.6 to 393.5 μm. Volume densities of basal (20.2%), prickle cell (55.6%), and cornified (24.2%) layers remained stable. The peak number of neutrophils were 6 cells/mm^2^ and the mononuclear cells were 44 cells/mm^2^. Collagen fibers (80%) and fibroblasts (14%) occupied the main volume of connective tissue. The one‐way ANOVA and the paired Student's t‐test were used for statistical analysis (P < 0.05).

Conclusion

Low‐level laser therapy did not accelerate the healing of oral mucosa after gingivoplasty. Lasers Surg. Med. 35:377–384, 2004. © 2004 Wiley‐Liss, Inc.


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