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Histological evaluations following 1,064-nm Nd:YAG laser resurfacing

✍ Scribed by Steven Dayan; John F. Damrose; Tapan K. Bhattacharyya; Steven Ross Mobley; Minu K. Patel; Kevin O'Grady; Steven Mandrea

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
262 KB
Volume
33
Category
Article
ISSN
0196-8092

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Background and Objectives

The long pulse 1,064‐nm Nd:YAG laser is used clinically to decrease rhytid formation. The dermal level at which this change occurs has not been established. This study attempts to answer these questions using a porcine skin model.

Study Design/Materials and Methods

Non‐randomized prospective experimental trial involving the domestic piglet treated serially with the long pulse 1,064‐nm Nd:YAG laser.

Results

Collagen formation occurred at the level of the reticular dermis. After one laser treatment, a significant level of collagen formation was induced in the reticular dermis compared to controls. The greatest gain was observed after four laser treatments. Energy levels of 20, 30, 40, and 50 J/cm^2^ were evaluated. Although not statistically significant, 30 J/cm^2^ had the greatest effect on collagen formation. However, at 50 J/cm^2^, marked ablative changes to the epidermis were observed.

Conclusions

The long pulse 1,064‐nm Nd:YAG laser induces collagen formation in the reticular dermis in porcine skin. Lasers Surg. Med. 33:126–131, 2003. © 2003 Wiley‐Liss, Inc.

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