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Histological evaluation of the intrahepatic biliary tree in intrahepatic cholesterol stones, including immunohistochemical staining against apolipoprotein A-1

✍ Scribed by Tetsuo Ohta; Takukazu Nagakawa; Toshiya Takeda; Luis Fonseca; Masahiro Kanno; Kazuhiro Mori; Masato Kayahara; Keiichi Ueno; Itsuo Miyazaki; Tadashi Terada


Book ID
102850935
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
971 KB
Volume
17
Category
Article
ISSN
0270-9139

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✦ Synopsis


Apolipoprotein A-1 is known to be one of inhibiting factors of cholesterol nucleation in bile, and decreased activity of apolipoprotein A-1 is considered to predispose cholesterol-supersaturated bile to formation of cholesterol crystals. To study the pathogenesis of the intrahepatic formation of cholesterol stones, we examined surgically resected liver specimens from six