✦ LIBER ✦

Histologic specificity of the effect of age at birth of first child on breast cancer risk

✍ Scribed by Alan S. Morrison

Publisher: John Wiley and Sons
Year: 1976
Tongue: French
Weight: 344 KB
Volume: 18
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.2910180602

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Slides of 531 breast cancers from Glamorgan, Wales, were classified according to the presence or absence of each of three histologic characteristics: stromal infiltration by linear strands of tumor cells, areas of intraductal carcinoma, and areas of lobular carcinoma in situ. The proportion of tumors with each of these characteristics was positively associated with age at first child‐birth. Increasing age at first birth had a strong positive effect on the incidence risk of tumors with any of these features, but only a small effect on risk of tumors with none. For porous women, the rate of breast cancer with or without linear strands, with or without areas of intraductal cancer, and without areas of lobular carcinoma in situ was lower than for nulliparous women. Parity appeared not to reduce the risk of tumors with areas of lobular carcinoma in situ.

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